I am also getting an i/o error. I did on an old version of ImgBurn so I've updated to the newest version, and still am getting the i/o error. Funny thing is, I never got errors prior to today using whatever cd media I had at the time. I ran in it test mode first, then tried to burn the iso:
I 11:25:29 ImgBurn Version 2.4.2.0 started!
I 11:25:29 Microsoft Windows XP Home Edition (5.1, Build 2600 : Service Pack 2)
I 11:25:29 Total Physical Memory: 916,464 KB - Available: 478,120 KB
I 11:25:29 Initialising SPTI...
I 11:25:29 Searching for SCSI / ATAPI devices...
I 11:25:30 Found 1 DVD-ROM and 1 DVD-ROM/CD-RW!
I 11:26:58 Operation Started!
I 11:26:58 Source File: C:\DOWNLOADS\xpsp3_5512.080413-2113_fi_x86fre_spcd.iso
I 11:26:58 Source File Sectors: 189,255 (MODE1/2048)
I 11:26:58 Source File Size: 387,594,240 bytes
I 11:26:58 Source File Volume Identifier: GRTMUPD_FI
I 11:26:58 Source File Application Identifier: CDIMAGE 2.52 (03/09/2004 TM)
I 11:26:58 Source File File System(s): ISO9660
I 11:26:58 Destination Device: [1:0:0] TEAC DW-224E-A A.2E (K:) (ATA)
I 11:26:58 Destination Media Type: CD-R (Disc ID: 97m26s66f)
I 11:26:58 Destination Media Sectors: 359,847
I 11:26:58 Write Mode: CD
I 11:26:58 Write Type: SAO
I 11:26:58 Write Speed: 2x
I 11:26:58 Test Mode: Yes
I 11:26:58 OPC: No
I 11:26:58 BURN-Proof: Enabled
I 11:26:59 Filling Buffer... (20 MB)
I 11:27:05 Writing LeadIn...
I 11:27:49 Writing Session 1 of 1... (1 Track, LBA: 0 - 189254)
I 11:27:49 Writing Track 1 of 1... (MODE1/2048, LBA: 0 - 189254)
I 11:38:16 Synchronising Cache...
I 11:38:44 Cycling Tray after Test Write...
I 11:38:46 Exporting Graph Data...
I 11:38:46 Graph Data File: C:\Documents and Settings\Mum\Application Data\ImgBurn\Graph Data Files\TEAC_DW-224E-A_A.2E_SUNDAY-AUGUST-30-2009_11-26_AM_97m26s66f_2x.ibg
I 11:38:46 Export Successfully Completed!
I 11:38:46 Operation Successfully Completed! - Duration: 00:11:47
I 11:38:46 Average Write Rate: 604 KB/s (4.0x) - Maximum Write Rate: 736 KB/s (4.9x)
I 11:53:07 Operation Started!
I 11:53:07 Source File: C:\DOWNLOADS\xpsp3_5512.080413-2113_fi_x86fre_spcd.iso
I 11:53:07 Source File Sectors: 189,255 (MODE1/2048)
I 11:53:07 Source File Size: 387,594,240 bytes
I 11:53:07 Source File Volume Identifier: GRTMUPD_FI
I 11:53:07 Source File Application Identifier: CDIMAGE 2.52 (03/09/2004 TM)
I 11:53:07 Source File File System(s): ISO9660
I 11:53:07 Destination Device: [1:0:0] TEAC DW-224E-A A.2E (K:) (ATA)
I 11:53:07 Destination Media Type: CD-R (Disc ID: 97m26s66f)
I 11:53:07 Destination Media Sectors: 359,847
I 11:53:07 Write Mode: CD
I 11:53:07 Write Type: SAO
I 11:53:07 Write Speed: 2x
I 11:53:07 Test Mode: No
I 11:53:07 OPC: No
I 11:53:07 BURN-Proof: Enabled
I 11:53:07 Filling Buffer... (20 MB)
I 11:53:07 Writing LeadIn...
I 11:54:25 Writing Session 1 of 1... (1 Track, LBA: 0 - 189254)
I 11:54:25 Writing Track 1 of 1... (MODE1/2048, LBA: 0 - 189254)
W 12:00:24 Failed to Write Sectors 107072 - 107103 - Reason: Write Error
W 12:00:24 Retrying (1 of 20)...
W 12:00:24 Retry Failed - Reason: Invalid Field in CDB
W 12:00:24 Retrying (2 of 20)...
W 12:00:24 Retry Failed - Reason: Invalid Field in CDB
W 12:00:24 Retrying (3 of 20)...
W 12:00:24 Retry Failed - Reason: Invalid Field in CDB
W 12:00:24 Retrying (4 of 20)...
W 12:00:24 Retry Failed - Reason: Invalid Field in CDB
W 12:00:24 Retrying (5 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (6 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (7 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (8 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (9 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (10 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (11 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (12 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (13 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (14 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (15 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (16 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (17 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (18 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (19 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
W 12:00:25 Retrying (20 of 20)...
W 12:00:25 Retry Failed - Reason: Invalid Field in CDB
E 12:04:42 Failed to Write Sectors 107072 - 107103 - Reason: Write Error
I 12:04:43 Synchronising Cache...
W 12:04:43 Synchronise Cache Failed! - Reason: Invalid Field in CDB
W 12:04:43 Retrying (1 of 3)...
W 12:04:43 Retry Failed - Reason: Invalid Field in CDB
W 12:04:43 Retrying (2 of 3)...
W 12:04:43 Retry Failed - Reason: Invalid Field in CDB
W 12:04:43 Retrying (3 of 3)...
W 12:04:43 Retry Failed - Reason: Invalid Field in CDB
E 12:04:47 Synchronise Cache Failed! - Reason: Invalid Field in CDB
W 12:04:50 User opted to skip the 'Close Track/Session/Disc' functions.
E 12:04:50 Failed to Write Image!
I 12:04:50 Exporting Graph Data...
I 12:04:52 Graph Data File: C:\Documents and Settings\Mum\Application Data\ImgBurn\Graph Data Files\TEAC_DW-224E-A_A.2E_SUNDAY-AUGUST-30-2009_11-53_AM_97m26s66f_2x.ibg
I 12:04:52 Export Successfully Completed!
E 12:04:52 Operation Failed! - Duration: 00:11:43
I 12:04:52 Average Write Rate: 347 KB/s (2.3x) - Maximum Write Rate: 704 KB/s (4.7x)