I am having a problem with some of the Blu-rays (BD-R - Verbatim/25GB) that I have burned. The video is absolutely perfect, but the audio will sporadically drop for a second and then return. Other than the audio drops, the BD-Rs are perfect. However, it's rather difficult to enjoy a movie when you constantly have the audio dropping out (i.e. I made a copy of The Princess and the Frog for my daughter and the audio would drop sporadically during the various musical numbers).
For what it's worth, I used AnyDVDHD to rip the movie, BD Rebuilder to compress it to fit onto a BD-R and then IMGBurn. Additionally, I tested the compressed version using TotalMedia Theatre in my attempts to blame BD Rebuilder and I did not have the audio drops when playing the same scenes.